Necrotizing soft tissue infection of the breast: bilateral presentation in a male patient

Necrotizing soft tissue infections (NSTIs) can affect any part of the body but are rarely seen in the breast. To date, most cases have presented unilaterally, and all published reports have occurred in female patients. We describe the first case of bilateral NSTI of the breasts in a male patient with history of mastitis and breast biopsies. He was successfully treated with antibiotics and bilateral mastectomy. A history of mastitis or instrumentation of the breast should raise suspicion for a necrotizing soft infection of the breast even in a male, in the setting of systemic and radiologic signs consistent with a necrotizing infection.